Blood pressure lowering efficacy of beta-1 selective beta blockers for primary hypertension
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چکیده
منابع مشابه
Beta-blockers for hypertension
BACKGROUND Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardial infarction. Beta-blockers were thought to have similar beneficial effects when used as first-line therapy for hypertension. Howev...
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BaCkground Beta-blockers refer to an assorted group of medications that block the action of endogenous catecholamines on beta-adrenergic receptors. The β1 and β2 receptors are the primary beta-adrenergic receptors in the human cardiovascular system. Betablockers differ in their β1/β2-receptor selectivity and vasodilatory properties. Based on this diversity, beta-blockers have been categorised i...
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BACKGROUND ACE inhibitors are widely prescribed for hypertension so it is essential to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE). OBJECTIVES To quantify the dose-related systolic and/or diastolic BP lowering efficacy of ACE inhibitors versus placebo in the treatment of primary hypertension. SEARCH STRATEGY We searche...
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Hypertension is a common condition in developed and developing nations, associated with cardiovascular complications and end organ damage, and yet its etiology remains largely elusive. It has long been recognized that satisfactory control of blood pressure reduces cardiovascular complications. Early trials, before the advent of drugs acting on the renin-aldosterone system, (RAS) revealed the th...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2016
ISSN: 1465-1858
DOI: 10.1002/14651858.cd007451.pub2